Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors

Figure 3

Inhibition activities against cell proliferation for compounds 6a–i at 40 μg/mL. Abbreviations: HepG2: human hepatocellular liver carcinoma cell line; MCF-7: human breast adenocarcinoma cell line; 5-FU: 5-fluorouracil, used as a positive control.