Research Article

Development and Validation of Stability Indicating HPTLC and HPLC Methods for Simultaneous Determination of Telmisartan and Atorvastatin in Their Formulations

Table 3

Results of robustness study by HPLC.

Parameter% RSD
TLMATV

Change in pH of mobile phase
pH 4.00.4120.845
pH 3.80.8500.567
pH 4.20.6430.730

Change in temperature
20°C0.8020.335
25°C0.5600.950
30°C0.3580.741

Change in flow rate
0.8 mL/min0.8410.863
1.0 mL/min0.9240.857
1.2 mL/min1.9841.732

Change in wavelength
2800.5370.870
2820.9601.005

TLM: Telmisartan; ATV: Atorvastatin.