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Journal of Chemistry
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2013
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Article
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Tab 3
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Research Article
Development and Validation of Stability Indicating HPTLC and HPLC Methods for Simultaneous Determination of Telmisartan and Atorvastatin in Their Formulations
Table 3
Results of robustness study by HPLC.
Parameter
% RSD
TLM
ATV
Change in pH of mobile phase
pH 4.0
0.412
0.845
pH 3.8
0.850
0.567
pH 4.2
0.643
0.730
Change in temperature
20°C
0.802
0.335
25°C
0.560
0.950
30°C
0.358
0.741
Change in flow rate
0.8 mL/min
0.841
0.863
1.0 mL/min
0.924
0.857
1.2 mL/min
1.984
1.732
Change in wavelength
280
0.537
0.870
282
0.960
1.005
TLM: Telmisartan; ATV: Atorvastatin.