Research Article
Synthesis of Novel 1,2,4-Triazole Derivatives as Antimicrobial Agents via the Japp-Klingemann Reaction: Investigation of Antimicrobial Activities
Table 4
Antimicrobial activities of the compounds (MIC, mg/mL) 4a–g.
| | Entry no. | S. typhii | B. pyogenes | A. niger | C. albicans |
| | 4a | 18.0 | 21.0 | 40.0 | 24.0 | | 4b | 12.0 | 10.0 | 65.0 | 42.0 | | 4c | 09.00 | 13.0 | 60.0 | 40.0 | | 4d | 14.0 | 09.00 | 72.0 | 43.0 | | 4e | 15.0 | 18.0 | 44.0 | 27.0 | | 4f | 16.0 | 22.0 | 38.0 | 25.0 | | 4g | 21.0 | 19.0 | 43.0 | 33.0 | | Gentamycin | 25 | 25 | — | — | | Amphotericin | — | — | 100 | 50 | | Control | DMSO | DMSO | DMSO | DMSO |
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