Research Article
Synthesis and Biological Evaluation of Some Novel Dithiocarbamate Derivatives
Table 2
% Inhibition potency of the compounds on AChE at 10−3–10−4 M concentrations.
| Comp. | Inhibition % | 10−3 M | 10−4 M |
| 4a | 16.95 | 16.45 | 4b | 16.21 | 14.36 | 4c | 41.93 | 12.98 | 4d | 31.39 | 9.78 | 4e | 41.48 | 11.47 | 4f | 9.54 | 8.37 | 4g | 7.56 | 2.42 | 4h | 8.58 | 1.97 | 4i | 15.56 | 1.02 | 4j | 15.55 | 1.49 | 4k | 12.11 | 3.01 | 4l | 6.31 | 3.86 | 4m | 9.47 | 2.43 | 4n | 12.11 | 2.17 | 4o | 28.81 | 9.31 | 4p | 37.78 | 2.36 | 4r | 7.65 | 7.43 | 4s | 7.40 | 5.10 | Donepezil | 98.37 | 92.31 |
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