Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery

Table 4

Validation of the Hypo 1 using the CatScramble program.

Validation number	Total cost	Correlation (𝑟)
Hypo 1	150.914	0.902269
Random trial_1	163.254	0.813374
Random trial_2	156.284	0.869499
Random trial_3	162.449	0.784895
Random trial_4	171.6	0.734126
Random trial_5	159.198	0.828584
Random trial_6	158.681	0.842351
Random trial_7	157.007	0.879218
Random trial_8	166.79	0.766941
Random trial_9	162.874	0.793253
Random trial_10	165.053	0.788512
Random trial_11	156.552	0.861163
Random trial_12	169.679	0.738177
Random trial_13	171.276	0.736358
Random trial_14	153.222	0.873299
Random trial_15	156.565	0.890657
Random trial_16	156.905	0.85654
Random trial_17	166.072	0.771533
Random trial_18	179.171	0.655302
Random trial_19	164.899	0.776163