Core Cross-linked Star Polymers for Temperature/pH Controlled Delivery of 5-Fluorouracil

Table 1

Preparation of linear macro-CTAs at 70°C in p-dioxane for 12 h.

Entries	Polymer	M : CTA : I	(target); (g/mol)	(GPC); (g/mol)	Ð; ()	Yield (wt%)
1	PolyNIPAAm	180 : 1 : 0.2	20,673	26,100	1.008	75
2	PolyNIPAAm	132 : 1 : 0.2	15,249	14,400	1.022	70
3	PolyNIPAAm	88 : 1 : 0.2	10,277	10,800	1.030	73
4	PolyNIPAAm	88 : 1 : 0.2	10,277	8,200	1.040	70
5	Poly(NIPAAm-co-4MBA5%)	180 : 1 : 0.2	21,510	22,000	1.157	78
6	Poly(NIPAAm-co-4MBA9%)	132 : 1 : 0.2	16,354	15,200	1.149	70

M: monomer; CTA: chain transfer agent; I: initiator.
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