Core Cross-linked Star Polymers for Temperature/pH Controlled Delivery of 5-Fluorouracil

Table 4

Hydrodynamic diameters and LCST values of star polymers, in PBS at pH 6 and in PBS at pH 7.4.

Entries	Star polymer	PBS, pH 6		LCST, pH 6	PBS, pH 7.4		LCST, pH 7.4
		(nm)	pdi	Temp. (°C)	(nm)	pdi	Temp. (°C)
1	[PolyNIPAAm-b-polyHA-EGDMA20	—	—	—	65.38 ± 4.4	0.397 ± 7e^−3	32
2	[PolyNIPAAm-b-polyHA-EGDMA10	—	—	30	108.8 ± 3.6	0.256 ± 0.02	30
3	[Poly(NIPAAm-co-4MBA9%)-b-polyHA-EGDMA20	62.74 ± 0.62	0.257 ± 1e^−3	36	94.68 ± 1.5	0.187 ± 8e^−3	46
4	[Poly(NIPAAm-co-4MBA5%)-b-polyHA-EGDMA10	112.4 ± 4.8	0.326 ± 0.03	36	171.03 ± 0.6	0.302 ± 0.02	40

Macro-CTA of = 12,780 g/mol. Macro-CTA of = 32,070 g/mol. Macro-CTA of = 21,730 g/mol. Macro-CTA of = 28,570 g/mol.