Fucofuroeckol-A from Eisenia bicyclis Inhibits Inflammation in Lipopolysaccharide-Induced Mouse Macrophages via Downregulation of the MAPK/NF-κB Signaling Pathway

Figure 2

Effect of FF on LPS-induced protein (a) and mRNA (b) expression of iNOS and COX-2 in RAW 264.7 macrophages. The cells were grown at 5 × 10⁵ cells/well and treated with various concentrations of FF for 1 h before LPS (1 μg/mL) treatment. After incubation for 12 h (RT-PCR) and 24 h (Western blot), cell lysates were collected and subjected to Western blot and RT-PCR analysis.

(a)

(b)