Purin-6-One Derivatives as Phosphodiesterase-2 Inhibitors

Figure 2

The interaction of BAY 60-7550 with the catalytic domain of PDE2 (PDB ID: 4HTX). The BAY compound is rendered with green color scheme. Residues that form key interactions with BAY compound are rendered with orange color scheme. The environmental protein surrounding is rendered in orange. For the convenience of display, some residues are not shown.