New Caffeic Acid Phenylethyl Ester Analogs Bearing Substituted Triazole: Synthesis and Structure-Activity Relationship Study towards 5-Lipoxygenase Inhibition

Figure 6

Inhibition of 5-LO products synthesis by analogs 8a-b, 10a, 10e, and 12g in stimulated human PMNL. Values are the means ± SEM of three independent experiments, each performed in quadruplicate; from control (diluent) as determined by one-way ANOVA with Dunnett’s multiple comparison test ().