FTIR Spectrophotometry as a Green Tool for Quantitative Analysis of Drugs: Practical Application to Amoxicillin

Table 1

Preparation of pellets for the recovery assay of the method of FT-IR spectrophotometry for amoxicillin.

	AMX sample (mg) (diluted 1 : 10 w/w in KBr)	AMX RS (mg) (diluted 1 : 10 w/w in KBr)	Amount of KBr (mg)^1	Final theoretical concentration (mg/pellet)
Sample	5.0	—	145.0	0.50
R1	5.0	3.0	142.0	0.80
R2	5.0	5.0	140.0	1.00
R3	5.0	7.0	138.0	1.20
Reference standard	—	5.0	145.0	0.50

¹Sufficient amount for the preparation of pellets with a total weight of 150 mg. AMX: amoxicillin; AMX RS: amoxicillin reference standard.