Assessment of Toxicity and Therapeutic Effects of Goose Bone in a Rat Model
Table 1
The effects of goose bone on relative organ weight.
Organs
Control
30 mg/kg
60 mg/kg
120 mg/kg
Heart
0.384 ± 0.01
0.359 ± 0.01
0.367 ± 0.01
0.320 ± 0.02
Kidney
0.781 ± 0.07
0.807 ± 0.03
0.801 ± 0.05
0.795 ± 0.07
Lung
0.671 ± 0.87
0.713 ± 0.14
0.657 ± 0.13
0.634 ± 0.02
Liver
3.732 ± 0.40
3.890 ± 0.26
3.849 ± 0.11
3.742 ± 0.45
Spleen
0.226 ± 0.01
0.233 ± 0.02
0.232 ± 0.01
0.211 ± 0.01
Caecum
0.276 ± 0.02
0.265 ± 0.04
0.257 ± 0.04
0.255 ± 0.05
Pancreas
0.129 ± 0.06
0.156 ± 0.04
0.172 ± 0.11
0.124 ± 0.06
Brain
0.864 ± 0.01
0.874 ± 0.05
0.871 ± 0.07
0.829 ± 0.15
Testes
0.113 ± 0.09
0.121 ± 0.08
0.118 ± 0.09
0.097 ± 0.06
Thymus
0.133 ± 0.01
0.149 ± 0.06
0.139 ± 0.07
0.147 ± 0.05
Caput
0.287 ± 0.07
0.268 ± 0.09
0.254 ± 0.05
0.276 ± 0.05
Cowper gland
0.151 ± 0.01
0.159 ± 0.01
0.156 ± 0.00
0.152 ± 0.01
Stomach
0.659 ± 0.03
0.630 ± 0.01
0.590 ± 0.03
0.608 ± 0.02
Ovary
0.075 ± 0.03
0.077 ± 0.01
0.070 ± 0.02
0.072 ± 0.03
Fallopian tube
0.306 ± 0.01
0.280 ± 0.01
0.282 ± 0.01
0.270 ± 0.01
Results are expressed as mean ± SD (n = 8). Nonsignificant changes were found when all treatment groups were compared against the control group () as determined using one-way ANOVA followed by Dunnett’s multiple comparison tests.