Physicochemical Contents, Antioxidant Activities, and Acute Toxicity Assessment of Selenium-Enriched Chinese Kale (Brassica oleracea var. alboglabra L.) Seedlings
Table 4
Hematological and biochemical values of rats treated with Chinese kale seedlings for acute toxicity administration.
Dose mg/kg b.w.
HB (g/dL)
Hct (%)
RBC (106/cm)
MCV (fL)
MCH (pg)
MCHC (%)
WBC (103/cm)
Neu (%)
Lym (%)
Control
16.8 ± 0.3
49.3 ± 0.5
8.2 ± 0.1
60.3 ± 1.0
20.3 ± 0.3
33.7 ± 0.3
2400 ± 594
7.5 ± 0.7
92.3 ± 0.8
R-KS 1250
16.7 ± 0.3
50.5 ± 0.3
8.6 ± 0.1
58.5 ± 1.2
19.4 ± 0.6
33.1 ± 0.4
2475 ± 460
6.8 ± 1.5
91.3 ± 2.4
R-KS 2500
15.8 ± 0.2
48.5 ± 0.3
8.4 ± 0.1
57.5 ± 0.7
18.8 ± 0.2
32.8 ± 0.3
1800 ± 141
10.5 ± 1.3
89.3 ± 1.3
R-KS 5000
16.8 ± 0.1
50.3 ± 0.5
8.2 ± 0.3
57.0 ± 2.9
20.5 ± 0.7
34.0 ± 0.6
2025 ± 322
9.0 ± 4.5
89.5 ± 5.9
Se-KS 1250
16.8 ± 0.3
50.5 ± 0.7
8.5 ± 0.2
59.5 ± 1.8
19.9 ± 0.6
33.4 ± 0.5
1650 ± 206
7.3 ± 1.9
90.5 ± 1.7
Se-KS 2500
16.5 ± 0.5
49.3 ± 1.3
8.4 ± 0.1
58.0 ± 0.8
19.6 ± 0.4
33.7 ± 0.2
1600 ± 339
7.0 ± 1.1
95.8 ± 1.7
Se-KS 5000
16.5 ± 0.3
49.5 ± 1.0
8.6 ± 0.3
57.5 ± 0.7
19.4 ± 0.6
33.4 ± 0.3
2500 ± 635
4.0 ± 1.2
94.0 ± 1.5
Dose (mg/kg b.w.)
BUN (mg/dL)
CREA (mg/dL)
UA (mg/dL)
TP (mg/dL)
AST (U/L)
ALT (U/L)
ALP (U/L)
Control
21 ± 1
0.63 ± 0.02
0.85 ± 0.10
6.15 ± 0.18
74 ± 11
26 ± 1
109 ± 5
R-KS 1250
24 ± 2
0.85 ± 0.12
2.00 ± 0.36
5.83 ± 0.09
94 ± 24
30 ± 2
142 ± 16
R-KS 2500
24 ± 1
0.78 ± 0.05
1.90 ± 0.56
6.38 ± 0.19
101 ± 19
29 ± 2
117 ± 8
R-KS 5000
22 ± 1
0.75 ± 0.06
1.85 ± 0.71
6.38 ± 0.07
104 ± 13
25 ± 3
104 ± 14
Se-KS 1250
21 ± 1
0.80 ± 0.06
1.58 ± 0.25
7.05 ± 0.25
62 ± 12
31 ± 3
144 ± 14
Se-KS 2500
23 ± 1
0.68 ± 0.05
0.73 ± 0.11
6.75 ± 0.21
102 ± 9
24 ± 1
127 ± 11
Se-KS 5000
23 ± 4
0.58 ± 0.11
1.28 ± 0.48
6.50 ± 0.17
105 ± 38
32 ± 3
147 ± 14
Values are mean ± SEM for 4 rats in each group. HB = hemoglobin; Hct = hematocrit; RBC = red blood cell; MCV = mean cell volume; MCH = mean cell hemoglobin; MCHC = mean corpuscular hemoglobin concentration; WBC = white blood cell; Neu = neutrophils; Lym = lymphocytes. Values are mean ± SEM for 4 rats in each group. BUN = blood urea nitrogen; CREA = creatinine; UA = uric acid; TP = total protein; AST = aspartate aminotransferase; ALT = alanine aminotransferase; ALP = alkaline phosphatase.
