Quantification of the Nucleophilicities of 3-X-Thiophenes: Highlighting the Hyperortho Correlation

Table 3

Nucleophilicity parameters N of 3-X-substituted thiophenes in acetonitrile at 20°C.

	σ^+	N	Reference
OCH3	−0.78	3.06	[6]
OC2H5	−0.81	3.69	[16]
CH3	−0.31	2.38	This work
H	0.00	1.79	This work
Br	0.15	1.20	This work
NH2	−1.30	4.62	Estimated
CF3	0.61	0.23	Estimated
CN	0.66	0.13	Estimated
NO2	0.79	−0.17	Estimated