SERS Platform Based on Bimetallic Au-Ag Nanowires-Decorated Filter Paper for Rapid Detection of miR-196ain Lung Cancer Patients Serum

Figure 5

(a) SERS spectra of 5-FAM obtained before and after hairpin DNA hybridization at various concentrations of miR-196a in PBS. (b) The calibration curve of SERS intensities of ΔI₁₃₃₄ versus the miRNA concentration in PBS buffer. (c) Corresponding SERS spectra of 5-FAM collected before and after hairpin DNA hybridization by various concentrations of miR-196a in serum. (d) The calibration curve of SERS intensities of ΔI₁₃₃₄ versus the miRNA concentration in serum. The red scale bars represent 5000 a.u.

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