Research Article

Optimized Extraction Method for Kleeb Bua Daeng Formula with the Aid of the Experimental Design

Table 1

Box–Behnken design for the optimization of extraction conditions.

FactorSymbolLevels
−101

Type of solventAEthyl acetateEthanolMethanol
Number of extraction times (times)B124
Material-to-solvent ratio (g/ml)C1 : 31 : 61 : 9