Synthesis, Molecular Docking, MEP and SAR Analysis, ADME-Tox Predictions, and Antimicrobial Evaluation of Novel Mono- and Tetra-Alkylated Pyrazole and Triazole Ligands

Table 2

MIC (in µM) and MBC (in µM) values of active compounds 12 and 13 against the bacterial strains L. monocytogenes, E. coli, S. aureus, and C. freundii.

Entry		L. monocytogenes	E. coli	S. aureus	C. freundii
12	MIC	300	300	300	100
	MBC	300	300	300	200
	MBC/MIC	1	1	1	2
13	MIC	500	500	400	300
	MBC	800	500	500	400
	MBC/MIC	1.6	1	1.25	1.3