Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety

Table 1

The in vitro antifungal activities against Phomopsis sp., B. dothidea, and B. cinerea of the target compounds 4a–4q at 50 µg/mL.

Compounds	Inhibition rate (%)
	B. dothidea	Phomopsis sp.	B. cinerea
4a	90.8 ± 1.1	63.4 ± 2.1	93.3 ± 1.2
4b	79.2 ± 1.2	57.0 ± 1.3	83.6 ± 1.4
4c	67.5 ± 1.1	50.5 ± 1.8	72.0 ± 1.0
4d	64.5 ± 1.9	60.2 ± 2.1	66.6 ± 1.2
4e	24.6 ± 1.5	46.0 ± 1.4	56.8 ± 1.4
4f	94.3 ± 1.4	80.6 ± 2.0	91.7 ± 2.3
4g	76.8 ± 1.1	79.1 ± 1.2	86.8 ± 1.7
4h	46.5 ± 2.3	56.1 ± 2.1	55.2 ± 2.6
4i	32.1 ± 2.4	34.4 ± 1.1	39.6 ± 1.1
4j	85.9 ± 1.9	61.0 ± 2.1	81.3 ± 3.2
4k	70.9 ± 1.2	51.2 ± 1.8	75.2 ± 1.8
4l	62.9 ± 2.5	45.1 ± 2.2	66.8 ± 2.3
4m	53.5 ± 1.5	56.2 ± 1.1	56.0 ± 1.8
4n	43.4 ± 1.8	46.1 ± 2.1	53.8 ± 1.2
4o	93.5 ± 1.3	89.0 ± 1.0	96.7 ± 2.2
4p	70.8 ± 1.1	72.1 ± 1.2	83.8 ± 1.0
4q	98.5 ± 1.3	92.0 ± 1.0	97.6 ± 2.2
Pyrimethanil	84.4 ± 2.1	85.1 ± 1.4	82.8 ± 1.4