3,5-Dinitrobenzoate and 3,5-Dinitrobenzamide Derivatives: Mechanistic, Antifungal, and In Silico Studies

<div>Synthesis of esters and amides derived from 3,5-dinitrobenzoic acid: (a) ROH, H2SO4, reflux; (b) Et3N, RX, acetone, reflux; (c) ROH, THF, TPP, DIAD, 0°C to r.t. (d) (I) SOCl2, reflux; (II) ROH, CH2Cl2, 0°C to r.t. (e) (I) SOCl2, reflux; (II) RNH2, Et3N, CH2Cl2, 0°C to r.t.</div>

Journal of Chemistry

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Scheme 1

Scheme 1: 3,5-Dinitrobenzoate and 3,5-Dinitrobenzamide Derivatives: Mechanistic, Antifungal, and In Silico Studies