Research Article
Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex
Figure 3
(a) CD spectra of CT-DNA (0.1 mM) in the presence of DBPP at different [BPP]/[DNA] molar ratios after incubation at 37°C for 24 h in buffer (5.0 mM Tris-HCl, 50 mM NaCl, pH 7.4), and (b) agarose gel electrophoresis patterns of pUC19 plasmid DNA incubated with DBPP at 37°C for 24 h Lane 1, DNA control, lanes 2–7, ri = 0.30, 0.60, 0.90, 1.20, 1.50, and 1.60, respectively.
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