Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex

Table 1

Relative cellular viability of DBPP for 24 h^a.

Cell	Relative cellular viability at 50.0 μM concentration	Relative cellular viability at 100.0 μM concentration
MG-63	100.0% ± 2.5%	85.9% ± 1.8%
U2OS	85.8% ± 1.6%	55.7% ± 3.0%
HeLa	100.0% ± 1.1%	100.0% ± 1.6%
MCF-7	100.0% ± 0.9%	100.0% ± 3.8%

^aRelative cellular viability of cisplatin toward MG-63, U2OS, HeLa, and MCF-7 at 10.0 μM concentration for 24 h is 59.0% ± 1.0%, 52.1% ± 2.2%, 48.5% ± 1.0%, and 51.2% ± 1.2%, respectively.