IL-2 Flexible Loops Might Play a Role in IL-2 Interaction with the High-Affinity IL-2 Receptor: A Molecular Dynamics (MD) Study

Figure 2

Ten frames each obtained every 10 ns for the 100 ns MD simulations were aligned together using ribbon representation for WT IL-2, IL-2m, or IL-2m2. The IL-2 loops were rigid in IL-2m and IL-2m2 compared to WT IL-2.