Research Article

Antitrypanosomal and Anthelminthic Properties of Ethanol Extracts of Carica papaya Linn. and Ceiba pentandra (L) Gaertn.

Table 2

In vitro antitrypanosomal activities of crude extracts against T.b. brucei.

Plant speciesIC50 (μg/mL)Selectivity index
T.b. bruceiJurkat cell line

Coptis japonica13.94
PPSe23.329.890.42
PPLe33.6620.340.60
CPSe11.706.240.53
CPLe20.3821.381.05

PPSe = ethanol extract of Carica papaya stem bark; PPLe = ethanol extract of C. papaya leaves; CPSe = ethanol extract of Ceiba pentandra stem bark; CPLe = ethanol extract of C. pentandra leaves; Coptis japonica = positive control.