Synthesis and Bioactivity Evaluation of Novel Thiochroman-4-One Derivatives Incorporating Carboxamide and 1, 3, 4-Thiadiazole Thioether Moieties

Table 3

The antifungal activity of the target compounds 5a–5o against B. cinerea, V. dahliae, and F. oxysporum at 50 μg/mL.

Compounds	Inhibition rate (%)
	B. cinerea	V. dahliae	F. oxysporum
5a	0	0	2 ± 1.01
5b	17 ± 3.26	8 ± 1.21	5 ± 1.65
5c	21 ± 1.14	15 ± 2.96	12 ± 1.26
5d	0	2 ± 1.32	0
5e	0	0	0
5f	0	0	0
5g	48 ± 4.02	24 ± 1.69	16 ± 2.21
5h	55 ± 1.29	36 ± 2.95	26 ± 1.54
5i	0	0	0
5j	0	0	0
5k	0	12 ± 1.56	0
5l	61 ± 1.23	45 ± 1.95	32 ± 1.65
5m	69 ± 2.24	54 ± 1.25	40 ± 1.65
5n	0	0	0
5o	9 ± 1.94	6 ± 2.67
Carbendazim	57 ± 2.19	79 ± 3.18	100