Research Article

Changes of Cell Adhesion Molecules and T Cell Subset Populations in Acute Myeloid Leukemia Patients Undergoing Intravenous Administration of Cytarabine Supplemented with Idarubicin

Table 2

The proportions of CD4+, CD8+, and CD4+/CD8+ ratio in peripheral blood in AML patients following intravenous administration of cytarabine supplemented with either idarubicin or daunorubicin.

GroupCaseTimeCD3+ (%)CD4+ (%)CD8+ (%)CD4+/CD8+

Control group44Pretreatment59.15 ± 6.9730.14 ± 3.8734.15 ± 3.410.79 ± 0.08
Posttreatment62.74 ± 6.0335.87 ± 3.7232.96 ± 3.491.12 ± 0.12
t8.1256.1930.9413.618
0.0010.0070.0860.029
Study group44Pretreatment59.17 ± 6.9930.27 ± 3.9334.11 ± 3.490.81 ± 0.09
Posttreatment73.80 ± 8.51a39.91 ± 4.76a29.74 ± 2.35a1.39 ± 0.19a
t12.1197.3745.1744.396
0.0010.0010.0180.027

The letter a indicates compared to the control group.