Research Article

Changes of Cell Adhesion Molecules and T Cell Subset Populations in Acute Myeloid Leukemia Patients Undergoing Intravenous Administration of Cytarabine Supplemented with Idarubicin

Table 3

The proportions of CD4+IL-10 Tregs and CD4+CD25+CD127Foxp3+ Tregs in peripheral blood in AML patients following intravenous administration of cytarabine supplemented with either idarubicin or daunorubicin.

GroupCaseTimeCD4+IL-10 Tregs (%)CD4+CD25+CD127Foxp3+ Tregs (%)

Control group44Pretreatment27.75 ± 3.9723.31 ± 3.87
Posttreatment23.47 ± 2.5319.89 ± 1.75
t6.0315.341
<0.001<0.001
Study group44Pretreatment28.11 ± 3.6323.07 ± 3.93
Posttreatment20.40 ± 2.04a18.28 ± 1.43a
t12.2807.597
<0.001<0.001