Copper-Catalyzed Hydroboration of Enamides with Bis(pinacolato)diboron: Promising Agents with Antimicrobial Activities

Table 7

Minimum inhibitory concentration (MIC) of compounds 5-6 expressed in mg/ml, against L. monocytogenes, S. typhimurium, and S. aureus.

Tested compounds (300 μg/mL)^#	Listeria monocytogenes ATCC 1911	Staphylococcus aureus ATCC 6538	Salmonella typhimurium ATCC 14028
5a	0.156	0.136	0.126
5b	0.147	0.146	0.136
5c	0.312	0.211	0.310
5d	0.322	0.212	0.215
5e	0.332	0.215	0.323
6a	1.25	1.26	1.20
6b	2.5	2.23	2.3
6c	0.625	0.615	0.525
6d	1.25	1.22	0.915
6e	2.5	2.1	0.923
Ampicillin^a	0.002