In Vitro and In Silico Analysis of Bergenia ciliata and Mimosa pudica for Inhibition of α-Amylase

Table 5

Physiochemical and drug-likeness properties of compounds.

Compounds	Molecular weight g/mol	Hydrogen bond acceptors (HBA)	Hydrogen bond donors (HBD)	logP	Molar refractivity	Drug-likeness
Gallic acid	170.12	5	4	0.21	39.47	Yes; 0 violation
β-sitosterol	456.74	2	0	7.63	142.97	Yes; 1 violation
Bergenin	328.27	9	5	−0.72	72.80	Yes; 0 violation
Gallicin	184.15	5	3	0.57	43.79	Yes; 0 violations
Catechin	290.27	6	5	0.85	74.33	Yes; 0 violation
Tannic acid	1701.21	46	25	4.84	351.51	—
Galloylepicatechin	442.37	10	7	1.25	110.4	Yes; 1 violation
Galloylcatechin	442.37	10	7	1.44	110.04	Yes; 1 violation
Stigmasterol	412.69	1	1	6.97	132.75	Yes; 1 violation
Mimosine	198.18	5	3	−1.96	48.08	Yes; 0 violation
Betulinic acid	456.7	3	2	6.13	136.91	Yes; 1 violation
Mimopudine	337.33	8	5	−2.64	82.79	Yes; 0 violation
Quercetin	302.24	7	5	1.23	78.03	Yes; 0 violation
Avicularin	434.35	11	7	0.19	104.19	No; 2 violations
Allantoin	158.12	3	4	−1.85	39.55	Yes; 0 violation
p-Coumaric acid	164.16	3	2	1.26	45.13	Yes; 0 violation
2-hydroxymethyl-chroman-4-one	178.18	3	1	1.13	46.98	Yes; 0 violation