Development and Evaluation of a Novel Polymer Drug Delivery System Using Cromolyn-Polyamides-Disulfide using Response Surface Design

Table 5

ANOVA data of LE.

Source	DF	Adj SS	Adj MS	F value	T value	VIF	value
Model	10	6173.26	617.33	58.25	—	—	0.001
Linear	4	3771.58	942.89	88.97	—	—	0.001
Drug	1	2819.09	2819.09	266.00	16.31	1.20	0.001
FeCl3	1	1162.33	1162.33	109.67	−10.47	1.34	0.001
Polymer	1	125.90	125.90	11.88	−3.45	1.31	0.002
pH	1	39.15	39.15	3.69	−1.92	1.22	0.064
2-Way interaction	6	1200.79	200.13	18.88	—	—	0.001
DrugFeCl3	1	755.44	755.44	71.28	−8.44	1.16	0.001
Drugpolymer	1	131.92	131.92	12.45	−3.53	1.43	0.001
DrugpH	1	33.43	33.43	3.15	1.78	1.18	0.086
FeCl3polymer	1	139.76	139.76	13.19	3.63	1.22	0.001
FeCl3pH	1	24.20	24.20	2.28	−1.51	1.11	0.141
PolymerpH	1	21.16	21.16	2.00	−1.41	1.11	0.168
Error	31	328.54	10.60	—	—	—	—
Total	41	6501.81	—	—	—	—	—