Anti-Inflammatory Potentials of β-Ketoester Derivatives of N-Ary Succinimides: In Vitro, In Vivo, and Molecular Docking Studies

Figure 3

Percent inhibition produced by compound D (100 mg/kg) and chlorpheniramine maleate (25 mg/kg) in the histamine-induced paw edema model in mice. Each percent point represents the mean ± SEM for a group of 8 mice. Data were analyzed by Student’s t-test. Asterisks show significant values. , , and ; n.s, not significant.