Simultaneous Determination of Six Components in Beagle Dog Plasma by UPLC-MS/MS and Its Application to a Comparative Pharmacokinetic Study of Three Different Yuanhu Zhitong Preparations

Figure 1

Chemical structures of the analytes and IS. Corydaline, Cde; tetrahydropalmatine, Thp; tetrahydroberberine, Thb; tetrahydrocoptisine, Thc; byakangelicin, Bcin; byakangelicol, Bcol; promethazine hydrochloride, IS.