Chemistry and Antifungal Activity of Homoisoflavonoids

Table 1

Antifungal activity of homoisoflavonoids.

Antifungal test	Microorganism	Homoisoflavonoid	Result	Reference
Agar cup bioassay	(a) C. albicans (MTCC 3017),; (b) Aspergillus niger (MTCC 281)		(a) Inhibitory zone 8 mm at 100 μg/mL and 11 mm at 150 μg/mL; (b) Inhibitory zone 7 mm at 100 μg/mL and 10 mm at 150 μg/mL	[11]
Agar diffusion method	C. albicans Ca 54		MIC > 128 μg/mL	[10]
Agar cup bioassay method	C. albicans; A. niger		Inhibitory zone 5–15 cm at 100 μg/mL or 150 μg/mL	[26]
Progressive double dilution method	C. albicans		MIC = 50 μg/mL	[27]
Microdilution method	C. albicans (ATCC 90028), C. albicans (ATCC 60193), C. tropicalis (ATCC 13803), C. krusei (ATCC 6258), C. parapsilosis (ATCC 22019), and C. glabrata (ATCC 90030)		MIC = 62.5 μg/mL against C. albicans (ATCC 90028), C. tropicalis (ATCC 13803), and C. krusei (ATCC 6258)	[28]