Research Article
Synthesis, Characterization, and Biological Evaluation of Some Isoindole-1,3-(2H) Dione Derivatives
Table 10
Antiproliferative effect of studied compounds on HCT-116 cell line.
| | Compound number | Antiproliferative effect % on HCT-116 cell line | IC50 (μmol/mL) | | Conc. (μg/mL) | 62.5 | 125 | 250 | 500 | 1000 |
| | Compound 1 | | 0 | 21.317 | 28.723 | 39.546 | 46.154 | >3.39 | | Compound 2 | 20.5 | 35.8 | 38.2 | 44.8 | 50.25 | 1.941 | | Compound 3 | 36.098 | 48.232 | 48.126 | 50.715 | 54.432 | 0.651 |
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Compound 1: 0.001; compound 2: 0.001; compound 3: 0.001.
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