Synthesis, Characterization, and Biological Evaluation of Some Isoindole-1,3-(2H) Dione Derivatives

Table 13

Cell death assay of Caco-2 cells untreated and treated with studied compounds.

Cell death assay in Caco-2 line
Compound number	Concentration (μg/mL)	R1% late apoptotic cells	R2% live cells	R3% early apoptotic cells	R4% necrotic cells
Negative control	—	7.33	90.08	2.06	0.51
Compound 1	1000	12.94	74.04	12.22	0.95
Compound 2	500	53.52	25.75	20.48	0.25
Compound 3	500	89.04	5.65	5.04	0.29