Research Article
Synthesis, Characterization, and Biological Evaluation of Some Isoindole-1,3-(2H) Dione Derivatives
Table 4
Physiochemical properties of compounds.
| Compound no. | Compound name | Molecular formula | MW | Purity (%) | M.P. (°C) | Yield (%) |
| 1 | 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid | C17H13NO4 | 295.29 | 99.50 | 172-173 | 82–88 | 2 | 3-Phenyl-2-(4,5,6,7-tetrachloro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid | C17H9Cl4NO4 | 433.07 | 99.55 | 265.5–269 | 78–80 | 3 | 3-Phenyl-2-(4,5,6,7-tetrabromo-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid | C17H9Br4NO4 | 610.87 | 99.70 | 300–302 | 60–63 |
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Melting with degradation. |