Research Article

Synthesis, Characterization, and Biological Evaluation of Some Isoindole-1,3-(2H) Dione Derivatives

Table 4

Physiochemical properties of compounds.

Compound no.Compound nameMolecular formulaMWPurity (%)M.P. (°C)Yield (%)

12-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acidC17H13NO4295.2999.50172-17382–88
23-Phenyl-2-(4,5,6,7-tetrachloro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acidC17H9Cl4NO4433.0799.55265.5–26978–80
33-Phenyl-2-(4,5,6,7-tetrabromo-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acidC17H9Br4NO4610.8799.70300–30260–63

Melting with degradation.