Synthesis, Characterization, and Biological Evaluation of Some Isoindole-1,3-(2H) Dione Derivatives

Table 9

Antiproliferative effect of studied compounds on Caco-2 cell line.

Compound number	Antiproliferative effect % on Caco-2 cell line						IC50 (μmol/mL)
	Conc. μg/mL	62.5	125	250	500	1000
Compound 1		42.591	42.748	54.932	62.768	68.77	0.556
Compound 2		48.85	52.25	60.85	65.8	70.5	0.215
Compound 3		48.69	64.12	68	73.11	73.26	0.080

Compound 1: 0.001; compound 2: 0.001; compound 3: 0.001.