Inhibition of the SARS-CoV-2 Main Protease by Isoquercitrin <i>γ</i>-Cyclodextrin Inclusion Complex Formulations: A Biochemical and <i>In Silico</i> Study

<div>Inhibition by SunActive QCD™ of COVID-19 virus main protease M<sup>pro</sup>. The half-maximum inhibitory concentration (IC<sub>50</sub>) value was determined by nonlinear regression using 10 <i>μ</i>M substrate and 1 <i>μ</i>M enzyme with varying concentrations of SunActive QCD™. The structure of the active component of this formulation is shown on the right.</div>

Journal of Chemistry

fig1

Figure 1

Figure 1: Inhibition of the SARS-CoV-2 Main Protease by Isoquercitrin <i>γ</i>-Cyclodextrin Inclusion Complex Formulations: A Biochemical and <i>In Silico</i> Study 

Figure 1 | Inhibition of the SARS-CoV-2 Main Protease by Isoquercitrin γ-Cyclodextrin Inclusion Complex Formulations: A Biochemical and In Silico Study 