Inhibition of the SARS-CoV-2 Main Protease by Isoquercitrin γ-Cyclodextrin Inclusion Complex Formulations: A Biochemical and In Silico Study

Figure 2

Inhibition by SunActive formulations of Zika virus protease. The half-maximum inhibitory concentrations (IC₅₀) of SunActive DCD™ and SunActive QCD™ active components were determined by nonlinear regression using 20 μM substrate and 5 nM enzyme by varying concentrations of the inhibitors (SunActive DCD™ and SunActive QCD™). The structures of the active components of the inhibitors are shown on the right.

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