Research Article

Potential of Natural Antioxidants for Upregulating Apoptosis in Cervical Cancer Cells: A Cellular and Molecular Study

Table 2

Protein expressions of caspase3, p53, Bax, and Bcl2 relative to those of B-actin.

Caspase3p53BaxBcl2Bax/Bcl2

Control0.67 ± 0.01g0.56 ± 0.02h0.55 ± 0.01h0.44 ± 0.01g1.26 ± 0.02i
Ge1.15 ± 0.02d0.91 ± 0.01e1.67 ± 0.02c0.7 ± 0.02c2.35 ± 0.02e
Qu1.08 ± 0.01e0.81 ± 0.01f1.52 ± 0.01d0.59 ± 0.01e2.61 ± 0.05d
Cit0.82 ± 0.01f0.61 ± 0.02g1.43 ± 0.02e0.43 ± 0.01g3.67 ± 0.03a
Cis1.42 ± 0.03c1.38 ± 0.02c2.35 ± 0.02b0.84 ± 0.02a2.84 ± 0.01c
Ge + Cit0.83 ± 0.02f0.65 ± 0.01g1.10 ± 0.02g0.65 ± 0.02d1.66 ± 0.03h
Ge + Qu0.84 ± 0.01f0.78 ± 0.01f1.17 ± 0.02f0.52 ± 0.02f2.27 ± 0.02f
Ge + Cit + Qu1.19 ± 0.01d1.13 ± 0.02d1.65 ± 0.01c0.75 ± 0.02b2.14 ± 0.02g
Ge + Qu + Cis1.49 ± 0.02b1.79 ± 0.02b2.37 ± 0.02b0.77 ± 0.01b3.06 ± 0.02b
Ge + Qu + Cit + Cis1.57 ± 0.03a2.02 ± 0.02a2.71 ± 0.03a0.87 ± 0.01a3.11 ± 0.01b

The Bax to Bcl2 ratio was also estimated. Letters show significance between cell groups. Results are expressed as the mean ± standard deviation. N = 3.