Potential of Natural Antioxidants for Upregulating Apoptosis in Cervical Cancer Cells: A Cellular and Molecular Study
Table 2
Protein expressions of caspase3, p53, Bax, and Bcl2 relative to those of B-actin.
Caspase3
p53
Bax
Bcl2
Bax/Bcl2
Control
0.67 ± 0.01g
0.56 ± 0.02h
0.55 ± 0.01h
0.44 ± 0.01g
1.26 ± 0.02i
Ge
1.15 ± 0.02d
0.91 ± 0.01e
1.67 ± 0.02c
0.7 ± 0.02c
2.35 ± 0.02e
Qu
1.08 ± 0.01e
0.81 ± 0.01f
1.52 ± 0.01d
0.59 ± 0.01e
2.61 ± 0.05d
Cit
0.82 ± 0.01f
0.61 ± 0.02g
1.43 ± 0.02e
0.43 ± 0.01g
3.67 ± 0.03a
Cis
1.42 ± 0.03c
1.38 ± 0.02c
2.35 ± 0.02b
0.84 ± 0.02a
2.84 ± 0.01c
Ge + Cit
0.83 ± 0.02f
0.65 ± 0.01g
1.10 ± 0.02g
0.65 ± 0.02d
1.66 ± 0.03h
Ge + Qu
0.84 ± 0.01f
0.78 ± 0.01f
1.17 ± 0.02f
0.52 ± 0.02f
2.27 ± 0.02f
Ge + Cit + Qu
1.19 ± 0.01d
1.13 ± 0.02d
1.65 ± 0.01c
0.75 ± 0.02b
2.14 ± 0.02g
Ge + Qu + Cis
1.49 ± 0.02b
1.79 ± 0.02b
2.37 ± 0.02b
0.77 ± 0.01b
3.06 ± 0.02b
Ge + Qu + Cit + Cis
1.57 ± 0.03a
2.02 ± 0.02a
2.71 ± 0.03a
0.87 ± 0.01a
3.11 ± 0.01b
The Bax to Bcl2 ratio was also estimated. Letters show significance between cell groups. Results are expressed as the mean ± standard deviation. N = 3.