Nano-Pd/Chitosan Composite: An Extremely Effective Catalyst to the Synthesis of Pyrazolyl Analogues through Suzuki–Miyaura Cross-Coupling Reactions in an Aqueous Medium

Table 2

Suzuki–Miyaura cross-coupling reaction of various substituted boronic acid (2a–l) with (3-chloro-4,5-dihydro-1H-pyrazol-1-yl)(2-fluorophenyl) methanone under the stabilized reaction condition.

Entries	Boronic acid	Temperatures (°C)	Time (min)	Products	Yields (%)	Melting points (°C)
1	2a	60	60	3a	94	254
2	2b	60	60	3b	72	265
3	2c	60	60	3c	76	246
4	2d	60	60	3d	68	242
5	2e	60	60	3e	71	288
6	2f	60	60	3f	76	263
7	2g	60	60	3g	82	293
8	2h	60	60	3h	94	282
9	2i	60	60	3i	82	258
10	2j	60	60	3j	66	269
11	2k	60	60	3k	73	266
12	2l	60	60	3l	66	260