A Novel Drug-Drug Salt of Naproxen and Vortioxetine: Synthesis, Characterization, and Solubility Study

Table 1

Crystallographic parameters of NAP-VOT.

	NAP-VOT
Chemical formula	C18H23N2S, C14H13O3
Formula sum	C32H36N2O3S
Formula weight	528.69
Crystal system	Monoclinic
Space group	P121/c1
a (Å)	22.6926 (14)
b (Å)	5.7544 (5)
c (Å)	22.7571 (13)
α (°)	90
β (°)	106.627 (6)
γ (°)	90
Z	4
(Å^3)	2847.4 (4)
Dcalc (g cm^−3)	1.233
M (mm^−1)	0.149
R1 [I > 2σ (I)]	0.1158
(all data, F^2)	0.2143
GOF	1.142
Largest diff. peak and hole (e·Å^−3)	0.468/−0.359
CCDC	2234586