Preparation and Characterization of Patuletin-Loaded Chitosan Nanoparticles with Improved Selectivity and Safety Profiles for Anticancer Applications

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left"> </td><td class="align_center">MCF-7 IC<sub>50 (<i>μ</i>M)</sub></td><td class="align_center">HCT 116 IC<sub>50 (<i>μ</i>M)</sub></td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">PT-CS-NP</td><td class="align_center">2.41</td><td class="align_center">1.86</td></tr><tr><td class="align_left">PT</td><td class="align_center">18.17</td><td class="align_center">7.95</td></tr><tr><td class="align_left">CS</td><td class="align_center">8.85</td><td class="align_center">4.7</td></tr><tr><td class="align_left">Sorafenib</td><td class="align_center">4.13</td><td class="align_center">7.55</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div><i>In vitro</i> antiproliferative activities of CS, PT, and PT-CS-NP against A549 and HCT 116 cell lines.</div>

Journal of Chemistry

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Table 2

Table 2: Preparation and Characterization of Patuletin-Loaded Chitosan Nanoparticles with Improved Selectivity and Safety Profiles for Anticancer Applications 

Table 2 | Preparation and Characterization of Patuletin-Loaded Chitosan Nanoparticles with Improved Selectivity and Safety Profiles for Anticancer Applications 