Research Article
In Vivo Antifungal Activity and Computational Studies of Some Azole Derivatives against Candida Albicans
Table 1
Chemical structures of investigated compounds and in vitro MIC (μg/ml) against clinical C. albicans (12, 13).
| | Entry | Chemical structure | MIC (12, 13) | MIC (in this study) |
| | 1 | | NT | 256 | | 2 | | 4 (12) | 1 | | 3 | | 0.5 (12) | 0.5 | | 4 | | 128 (12) | 1 | | 5 | | 16 (12) | 1 | | 6 | | 256 (12) | 256 | | 7 | | 64 (12) | 1 | | 8 | | 2 (12) | 1 | | 9 | | 256 (12) | 256 | | 10 | | 256 (12) | 128 | | 11 | | 256 (12) | 256 | | 12 | | 64 (11) | 4 | | 13 | | >256 (11) | G | | 14 | | >256 (11) | G | | 15 | | 64 (11) | 16 | | Fluconazole | | 1 (12) 256 (11) | 1 |
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NT: not tested, G: growth.
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