In Vivo Antifungal Activity and Computational Studies of Some Azole Derivatives against Candida Albicans

Table 3

The bonding energies (kcal/mol) of the tested compounds on CYP51 and DHFR target using AutoDock Vina.

Entry

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

Flu

5FSA

−8.2

−8.9

−9.5

−9.0

−8.8

−8.7

−8.4

−9.3

−8.6

−8.1

−8.3

−8.6

−7.8

−8.9

−8.2

−8.5

4HOF

−7.0

−7.5

−8.6

−7.2

−7.3

−7.4

−7.0

−8.1

−7.0

−7.0

−6.8

−7.6

−7.3

−7.6

−7.5

−6.8

Flu: fluconazole.