Synthetic 2-Nitrocinnamates: Investigation of the Antifungal Action against Candida Species

Scheme 1

Obtaining 2-nitrocinnamates. Reagents and conditions: (a) ROH, H₂SO_{4 (cat.)}, and reflux 3–5 h; (b) Et₃N, RX, acetone, and reflux 12–52 h; (c) perillyl alcohol, DEAD, TPP, room temperature, and 48 h.