Design and In Silico and In Vitro Evaluations of a Novel Nicotinamide Derivative as a VEGFR-2 Inhibitor

Figure 4

(a) MS, (b) 2D, and (c) 3D images of the targeted nicotinamide derivative occupying the main four parts of VEGFR-2 (hydrogen bonds = green dashed lines, electrostatic interactions = orange dashed lines, pi-pi interactions = deep pink dashed lines, and pi-alkyl interactions = light pink dashed lines).

(a)

(b)

(c)