Design and In Silico and In Vitro Evaluations of a Novel Nicotinamide Derivative as a VEGFR-2 Inhibitor

Figure 5

The RMSD plot of VEGFR-2 (a), the RMSD plot of the ligand (A the radius of gyration (c), the SASA plot (d), the number of hydrogen bonds (e), and the RMSF plot (f) of apo VEGFR-2 (blue) and holo VEGFR-2 and ligand complex (red). The RMSD plot (b) of the targeted nicotinamide derivative. The center of mass distance plot (g) of VEGFR-2 and the ligand.

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