Novel Phytosomal Formulation of Emblica officinalis Extracts with Its In Vivo Nootropic Potential in Rats: Optimization and Development by Box-Behnken Design

Table 1

Factors of the experimental design in each of the three levels areas.

Box-Behnken design (BBD)	Coded factors	Levels
Independent variables		−1	0	+1
Phospholipid: drug ratio (% w/w)	A	1	2	3
Temperature (°C)	B	40	50	60
Time (h)	C	1	2	3
Dependent variable	Y	Entrapment efficiency in %