Comparing the Effectiveness of S-Ketamine Combined with Sufentanil versus Sufentanil Alone for Postoperative Pain Management in Elderly Patients Undergoing Laparoscopic Radical Resection of Gastrointestinal Cancer: A Randomized Controlled Trial

Table 2

Postoperative parecoxib sodium consumption and PCIA compressions.

	F group (n = 32)	LSF group (n = 32)	SF group (n = 31)	Differences (97.5% CI) value), LSF group vs F group	Differences (97.5% CI) value), SF group vs F group
Parecoxib sodium consumption after surgery (mg)
48 h parecoxib sodium	60 [40, 120]	60 [40, 80]	40 [0, 40]	0 (−40, 40) [0.8625]	−40 (−40, 0) [0.0028]
0 to 6 h	60 [40, 110]	40 [40, 80]	40 [0, 40]	0 (−40, 40) [0.7174]	−40 (−40, 0) [0.0020]
6 to 12 h	0 [0, 40]	0 [0, 40]	0 [0, 0]	0 (0, 0) [0.4330]	0 (0, 0) [0.0267]
12 to 24 h	0 [0, 0]	0 [0, 0]	0 [0, 0]	0 (0, 0) [0.3291]	0 (0, 0) [0.0283]
24 to 48 h	0 [0, 0]	0 [0, 0]	0 [0, 0]	0 (0, 0) [0.7003]	0 (0, 0) [0.3289]
Number of PCIA compression after surgery (times)
48 h PCIA compression	8 [7.25, 9]	7 [6, 9.75]	5 [4, 7]	−1 (−2, 0) [0.1153]	−3 (−4, −2) [<0.0001]
0 to 6 h	5 [3, 5]	4 [3, 5]	3 [2, 4]	0 (−1, 1) [0.4847]	−1 (−2, 0) [0.0032]
6 to 12 h	2 [2, 3]	2 [1, 2]	1 [1, 2]	0 (−1, 0) [0.1463]	−1 (−1, 0) [0.0009]
12 to 24 h	1 [0, 2]	1 [0, 1]	1 [0, 1]	0 (−1, 0) [0.6218]	0 (−1, 0) [0.0673]
24 to 48 h	1 [0, 1]	0.5 [0, 1]	0 [0, 1]	0 (0, 0) [0.6567]	0 (−1, 0) [0.0743]

Data are represented as median (25^th–75^th interquartile range) and media difference (97.5% CI). The Mann−Whitney U test was employed to compare intervention groups to the F group. Following Bonferroni correction, significance thresholds ( values) were set at 0.03 for comparisons within the first 48 hours after surgery and 0.00625 for comparisons at each postoperative time point. in comparison to the F group.