Research Article

Factors Influencing Blood Concentration of Voriconazole and Therapeutic Drug Monitoring in Patients with Child–Pugh Class C Cirrhosis

Table 3

Results of logistic regression analysis of the influencing factors for trough plasma concentrations (Cmin) of voriconazole.

FactorsOR95% CI value

Maintenance dosage schedule0.045
 Regimen ARef
 Regimen B3.7531.029–13.694
SCr (mmol/L)0.9910.979–1.0040.182
Hemodialysis0.307
 YesRef
 No3.2790.336–31.987

Ref, reference; SCr, serum creatinine. Statistically significant ( value <0.05).